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Myriad Genetics : ウィキペディア英語版 | Myriad Genetics
Myriad Genetics, Inc. is an American molecular diagnostic company based in Salt Lake City, Utah, United States. Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease. This information is used to guide the development of new molecular diagnostic products that assess an individual's risk for developing disease later in life (predictive medicine), identify a patient's likelihood of responding to a particular drug therapy and tailor a patient's drug dose to ensure optimal treatment (personalized medicine), and assess a patient's risk of disease progression and disease recurrence (personalized medicine). The discovery of the breast cancer gene, BRCA1 was universally acclaimed as a monumental achievement: “There is no more exciting story in medical science.”〔Batt, Sharon. Patient No More: The Politics of Breast Cancer. p 176〕 Myriad was the subject of scrutiny after it became involved in a lawsuit over its patenting practices,〔〔(【引用サイトリンク】 url=http://www.patentlyo.com/files/myriad-opinion.pdf )〕 which led to the landmark Supreme Court decision ''Association for Molecular Pathology v. Myriad Genetics''. ==History== The global search for a genetic basis for breast and ovarian cancer began in earnest in 1988. In 1990, at an American Society of Human Genetics Meeting, a team of scientists led by Mary-Claire King, Ph.D., from University of California, Berkeley announced the localization through linkage analysis of a gene associated with increased risk for breast cancer (''BRCA1'') to the long arm of chromosome 17. In August 1994, Mark Skolnick and researchers at Myriad, along with colleagues at the University of Utah, the U.S National Institutes of Health (NIH), and McGill University sequenced ''BRCA1''.
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